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 Laboratory Science Seminars
( Available from June 2nd, 2008 to 2nd August, 2008 )
  • Seminar 1: “The Role of the Platelet in Cardiovascular Disease”
    George A. Fritsma, MS, MT (ASCP)
    Associate Professor, Pathology
    University of Alabama at Birmingham

    Provided will be an overview of platelet physiology, how platelets participate in chronic inflammation, and how this can lead to cardiac disease. Specific platelet markers of cardiac risk such as: receptor phenotype, hyperaggregability and aspirin resistance will be discussed. Other subjects covered will include: platelet receptors and activation pathways, how platelets participate in the early development of atherosclerotic plaque, platelet polymorphisms and pathologies that contribute to arterial thrombosis, and how platelets trigger atherothrombosis in the sclerotic artery.

  • Seminar 2: “Clostridium perfringens and RBC Hemolysis: A Case Study”
    Matthew Massmann, MT (ASCP), NREMT-P
    Clinical Laboratory Outreach Coordinator, RiverView Health Systems, Staff Paramedic
    County Emergency Medical Services
    Crookston, MN

    The extremely rare case of a patient with massive RBC hemolysis as a result of Clostridium perfringens will be presented. The speaker's unique dual role as an EMT and Medical Technologist will allow you to follow the case from initial presentation to its endpoint. Basic characteristics and causes of hemolytic anemias will be discussed, as well as characteristics of Clostridium perfringens that can lead to red blood cell hemolysis.

  • Seminar 3: “Point of Care Testing”
    Gayle Deobald, AS, Lori Sorenson, MLT (ASCP)
    Point of Care Coordinators, Mayo Clinic
    Rochester, MN

    Point of care testing (POCT) continues to grow within the healthcare industry. The presentation will cover the past, present and future of POCT. Included will be a discussion of where POCT is being used; government regulations; and situations that POCT is chosen over traditional lab methods.

  • Seminar 4: “Bioterrorism: A Laboratory Perspective”
    Randy Graham, MT (ASCP)
    State Laboratory Training Coordinator
    Emergency Preparedness and Response Unit
    Public Health Laboratory
    Minnesota Department of Health

    The use of infectious agents as weapons is perhaps as old as warfare itself. The anthrax attacks of 2001 are only the latest round in an activity that has been occurring for centuries. While these attacks are now years behind us and fading from popular memory, history has shown us that bioterrorism will continue to be perpetrated, and thus we must be prepared. This discussion will include several historic bioterrorism incidents, the current laboratory capabilities for bioterrorism preparedness and response in both the clinical and public health laboratories. Information about the laboratory diagnosis of several potential agents of bioterrorism is reviewed.

  • Seminar 5: “Parasitology Case Studies: Clues to the Laboratory Identification of Commonly Encountered Parasites”
    Elmer Koneman, M.D., Professor Emeritus
    University of Colorado School of Medicine
    Breckenridge, CO

    Presented are thirteen case studies highlighting the laboratory diagnosis of more commonly encountered tissue and blood parasites. Each case will discuss key pathological findings and laboratory presentations leading to an identification of the selected parasite. A series of rhetorical questions will be presented for the participant to ponder as each case presentation proceeds, with answers provided. When applicable, a brief review of relevant serological and molecular assays will also be discussed.

  • Seminar 6: “West Nile Virus-Past, Present and Future”
    Greg Larson, MS, MT (ASCP)
    White Earth Health Center Laboratory
    Ogema, MN

    West Nile continues to be a public health threat and clinical laboratory diagnosis plays a crucial role in disease detection. The presentation will examine the origins of the virus, viral ecology and classification. Disease pathogenesis, virulence factors and host responses to WNV will be discussed. Clinical manifestations, laboratory diagnosis, treatment

  • Seminar 7: “End Stage Renal Disease and Diabetes”
    Patrice Nadeau M.S. MT(ASCP), Medical Assistant Program Director
    Dakota County Technical College
    Rosemount, MN

    This presentation will provide a basic overview of diabetes, a discussion of the biochemical mechanisms of cellular damage in hyperglycemia, and prevention strategies for ESRD.

  • Seminar 8: “A Practical Approach to Lupus Anticoagulant Testing”
    Layna Cardel, MT (ASCP)
    Instructor in Laboratory Medicine
    Mayo College of Medicine Rochester, MN

    The diagnosis of the Lupus Anticoagulant (LAC) has been a confusing topic to laboratorians and clinicians alike. The effect of pre-analytical variables, reagent test choices, and the heterogeneity of the LAC itself all contribute to the difficulty in making this important diagnosis. This session will discuss terminology, review available tests for LAC and someof their limitations, recommended diagnostic criteria, and individual test results in specific case studies.

  • Seminar 9: “You oughta verify your results!”
    David Plaut, Plano, Texas

    A discussion of current issues in autoverification and autorelease in regard to the clinical laboratory.

  • Seminar 10: “An Overview of Molecular Diagnostics”
    Donald Shepley, MP (ASCP), MPH
    Lead Medical Technologist
    Tucson, AZ

    Molecular testing is a new and exciting area of the laboratory. The basics of several molecular tests will be discussed.

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LEND Program
Department of Pathology
School of Medicine & Health Sciences Room# 3131
501 N. Columbia Road Stop 9037
Grand Forks, ND 58202-9037
Tel: (701)777-4050. Fax: (701)777-2404
Email: lend@medicine.nodak.edu